Jingsong Cao Selected Research

EBI-907

2/2016	Discovery of EBI-907: A highly potent and orally active B-Raf(V600E) inhibitor for the treatment of melanoma and associated cancers.
1/2016	EBI-907, a novel BRAF(V600E) inhibitor, has potent oral anti-tumor activity and a broad kinase selectivity profile.

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Jingsong Cao Research Topics

Disease

7	Neoplasms (Cancer) 01/2023 - 01/2016
5	Obesity 05/2014 - 07/2003
2	Prostatic Neoplasms (Prostate Cancer) 04/2019 - 08/2018
2	Melanoma (Melanoma, Malignant) 01/2018 - 02/2016
2	Insulin Resistance 12/2011 - 10/2008
2	Cholestasis 08/2003 - 06/2002
1	Virus Diseases (Viral Diseases) 01/2023
1	Hypoglycemia (Reactive Hypoglycemia) 01/2021
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2021
1	Inflammation (Inflammations) 01/2021
1	progressive familial intrahepatic 1 Cholestasis 01/2021
1	Glycogen Storage Disease (Glycogenosis) 01/2021
1	Body Weight (Weight, Body) 01/2021
1	Liver Diseases (Liver Disease) 01/2021
1	Adult-onset citrullinemia type 2 01/2019
1	Chronic Kidney Failure (Chronic Renal Failure) 12/2017
1	Colitis 05/2016
1	B-Cell Lymphoma (Lymphoma, B Cell) 05/2016
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 05/2016
1	Marginal Zone B-Cell Lymphoma (MALT Lymphoma) 05/2016
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 05/2016
1	Colorectal Neoplasms (Colorectal Cancer) 01/2016
1	Infections 01/2013
1	Weight Loss (Weight Reduction) 12/2011
1	Metabolic Diseases (Metabolic Disease) 12/2011
1	Hypothyroidism 04/2009

Drug/Important Bio-Agent (IBA)

5	Messenger RNA (mRNA)IBA 01/2023 - 01/2013
2	EnzymesIBA 01/2021 - 12/2006
2	Lipid NanoparticlesIBA 01/2021 - 01/2019
2	salinomycinIBA 04/2019 - 08/2018
2	EBI-907IBA 02/2016 - 01/2016
2	Proteins (Proteins, Gene)FDA Link 12/2011 - 04/2004
1	RNA (Ribonucleic Acid)IBA 01/2023
1	Phosphatidylcholines (Phosphatidylcholine)IBA 01/2021
1	Glucose-6-Phosphatase (Glucose 6 Phosphatase)IBA 01/2021
1	Starch (Cornstarch)IBA 01/2021
1	Biomarkers (Surrogate Marker)IBA 04/2019
1	Aspartic Acid (Aspartate)FDA Link 01/2019
1	citrinIBA 01/2019
1	Codon (Codons)IBA 01/2019
1	Amino Acid Transport System X-AG (Glutamate Transporter)IBA 01/2019
1	Therapeutic UsesIBA 01/2019
1	5,5',6,6'- tetrachloro- 1,1',3,3'- tetraethylbenzimidazolocarbocyanineIBA 08/2018
1	EBI-1051IBA 01/2018
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2018
1	AZD 6244IBA 01/2018
1	ABO Blood-Group SystemIBA 12/2017
1	Dextran SulfateIBA 05/2016
1	mepazineIBA 05/2016
1	Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 ProteinIBA 05/2016
1	InflammasomesIBA 05/2016
1	Peptide Hydrolases (Proteases)FDA Link 05/2016
1	VemurafenibIBA 01/2016
1	Phosphotransferases (Kinase)IBA 01/2016
1	CholesterolIBA 05/2014
1	Poly I-CIBA 01/2013
1	Triglycerides (Triacylglycerol)IBA 12/2011
1	Acyl Coenzyme A (Acyl CoA)IBA 12/2011
1	Insulin (Novolin)FDA Link 12/2011
1	Diacylglycerol O-AcyltransferaseIBA 12/2011
1	Glucose (Dextrose)FDA LinkGeneric 12/2011
1	Cardiolipins (Cardiolipin)IBA 04/2009
1	Thyroid HormonesIBA 04/2009
1	Protein Isoforms (Isoforms)IBA 10/2008
1	Multidrug Resistance-Associated Protein 2IBA 08/2003
1	estradiol-17 beta-glucuronideIBA 08/2003
1	Dietary Fats (Dietary Fat)IBA 07/2003
1	BucladesineIBA 06/2002
1	S-(2,4-dinitrophenyl)glutathioneIBA 06/2002

Therapy/Procedure

3	Therapeutics 01/2021 - 01/2019
2	Liver Transplantation 01/2021 - 01/2019
1	Injections 01/2021
1	Kidney Transplantation 12/2017
1	Oral Administration 12/2011